Endometriosis – A Chronic Inflammatory Disease

Endometriosis – A Chronic Inflammatory Disease

Endometriosis is a chronic inflammatory disease in which endometrial cells grow outside the uterus.

📌 Prevalence:
🔹 Affects 6–10% of women of reproductive age.
🔹 Occurs in 50% of women with infertility and chronic pelvic pain.

Causes of Endometriosis

The exact cause of endometriosis remains unclear, but several risk factors have been identified:

Menstrual blood flow disorders
Hormonal and metabolic factors, including:

  • Obesity;
  • Early onset of the first menstruation;
  • Late menopause;
  • Short menstrual cycles;
  • Low birth weight.

Exposure to environmental toxins, such as:

  • Waste burning;
  • Industrial processes;
  • Consumption of meat and animal-derived products containing harmful substances.
Types of Endometriosis (Based on Location)

🔹 Peritoneal – lesions on the surface of the peritoneum.
🔹 Ovarian – cysts on the ovaries or fallopian tubes.
🔹 Deeply infiltrating – aggressive growth beyond the peritoneum, affecting organs such as the bladder.

Classification of Endometriosis by Severity

Stage I (Minimal) – small adhesions.
Stage II (Mild) – presence of endometrial cysts.
Stage III (Moderate) – adhesions in the broad and sacro-uterine ligaments, involvement of the ovaries and fallopian tubes, lesions in the recto-uterine pouch.
Stage IV (Severe) – lack of pelvic mobility, endometrial lesions in the vagina, cervix, appendix, and bladder.

Impact of Endometriosis on Fertility

Endometriosis can negatively affect fertility by:
❌ Adhesions that prevent ovulation and block the transport of the egg through the fallopian tube.
❌ Inflammation that interferes with embryo implantation and ovulation.

Symptoms of Endometriosis

🚩 Pain – the primary symptom, which can vary in nature:

  • Ovulation-related pain: dull, burning, with a feeling of heaviness.
  • Adhesion-related pain: sharp, pulling, stabbing.
🚩 Other symptoms:
  • Pain during intercourse;
  • Lower abdominal pain lasting more than 6 months during menstruation (66% of women);
  • Reduced fertility;
  • Painful bowel movements;
  •  Blood in urine or stool;
  •  Irregular or heavy menstrual bleeding.

Pain can mimic other conditions, and in some cases, endometriosis may be asymptomatic, making diagnosis challenging.

Treatment and the Role of Physical Activity

Although endometriosis is not curable, its symptoms can be managed. One effective method is regular physical activity, which has been proven to have a positive impact on pain regulation and overall well-being.

💡 In the next post, you will learn how physical activity plays a crucial role in pain management and what an appropriate workout plan should look like.

Stay tuned! 🎯

Questions?

Feel free to contact me 📞
I'm here for you 👋🤰