Endometriosis – A Chronic Inflammatory Disease

Endometriosis – A Chronic Inflammatory Disease

Endometriosis is a chronic inflammatory disease in which endometrial cells grow outside the uterus.

📌 Prevalence:
🔹 Affects 6–10% of women of reproductive age.
🔹 Occurs in 50% of women with infertility and chronic pelvic pain.

Causes of Endometriosis

The exact cause of endometriosis remains unclear, but several risk factors have been identified:

✅ Menstrual blood flow disorders
✅ Hormonal and metabolic factors, including:

  • Obesity;
  • Early onset of the first menstruation;
  • Late menopause;
  • Short menstrual cycles;
  • Low birth weight.

✅ Exposure to environmental toxins, such as:

  • Waste burning;
  • Industrial processes;
  • Consumption of meat and animal-derived products containing harmful substances.
Types of Endometriosis (Based on Location)

🔹 Peritoneal – lesions on the surface of the peritoneum.
🔹 Ovarian – cysts on the ovaries or fallopian tubes.
🔹 Deeply infiltrating – aggressive growth beyond the peritoneum, affecting organs such as the bladder.

Classification of Endometriosis by Severity

Stage I (Minimal) – small adhesions.
Stage II (Mild) – presence of endometrial cysts.
Stage III (Moderate) – adhesions in the broad and sacro-uterine ligaments, involvement of the ovaries and fallopian tubes, lesions in the recto-uterine pouch.
Stage IV (Severe) – lack of pelvic mobility, endometrial lesions in the vagina, cervix, appendix, and bladder.

Impact of Endometriosis on Fertility

Endometriosis can negatively affect fertility by:
❌ Adhesions that prevent ovulation and block the transport of the egg through the fallopian tube.
❌ Inflammation that interferes with embryo implantation and ovulation.

Symptoms of Endometriosis

🚩 Pain – the primary symptom, which can vary in nature:

  • Ovulation-related pain: dull, burning, with a feeling of heaviness.
  • Adhesion-related pain: sharp, pulling, stabbing.
🚩 Other symptoms:
  • Pain during intercourse;
  • Lower abdominal pain lasting more than 6 months during menstruation (66% of women);
  • Reduced fertility;
  • Painful bowel movements;
  •  Blood in urine or stool;
  •  Irregular or heavy menstrual bleeding.

❗ Pain can mimic other conditions, and in some cases, endometriosis may be asymptomatic, making diagnosis challenging.

Treatment and the Role of Physical Activity

✅ Although endometriosis is not curable, its symptoms can be managed. One effective method is regular physical activity, which has been proven to have a positive impact on pain regulation and overall well-being.

💡 In the next post, you will learn how physical activity plays a crucial role in pain management and what an appropriate workout plan should look like.

Stay tuned! 🎯

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